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In convalescent COVID-19 patients, significantly elevated SDC-1 levels were detected after a median of 88 days after symptom onset compared to healthy controls, whereas no difference was found when compared to SDC-1 levels of hospitalized patients undergoing acute COVID-19 disease (100)

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These wide-ranging effects explain why glutathione depletion has been associated with accelerated aging, increased disease susceptibility, impaired detoxification capacity, and compromised immune responses